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Overview on acute-on-chronic liver failure

Jing Zhang,Shan Gao,Zhongping Duan,Ke-Qin Hu

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 1-17 doi: 10.1007/s11684-016-0439-x

Abstract:

Liver failure (LF) is defined as severe dysfunction in hepatic synthesis, detoxification, and metabolismLF can be classified into acute LF, acute-on-chronic LF (ACLF), and chronic LF.

Keywords： liver failure     chronic liver failure     acute-on-chronic liver failure     diagnosis     prognosis     treatment    

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Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 250-253 doi: 10.1007/s11684-014-0333-3

Abstract:

The clinical data of a patient with acute-on-chronic liver failure were analyzed retrospectively.His liver function deteriorated, yielding Child-Pugh grade C and reaching a model for end-stage liverperiod; this condition was complicated with highly active variceal bleeding and coagulation system failurePiggyback orthotopic liver transplantation was performed as the final treatment.

Keywords： acute-on-chronic liver failure     submassive necrosis     viral hepatitis B     esophageal variceal bleeding     liver    

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Correlation between viral load and liver cirrhosis in chronic hepatitis B patients

Lili LIU MM , Jiyao WANG MD , Weimin SHE MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 271-276 doi: 10.1007/s11684-009-0054-1

Abstract: between hepatitis B virus (HBV) DNA levels during the course and the progression to cirrhosis with chronicA total of 239 chronic hepatitis B patients confirmed by liver biopsy between 2001 and 2007 were followedProgression to cirrhosis in chronic hepatitis B patients is correlated with HBV-DNA levels during follow-up

Keywords： hepatitis B     chronic     viral load     liver cirrhosis    

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Advances in some common chronic liver diseases

Ke-Qin Hu

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 127-128 doi: 10.1007/s11684-014-0341-3

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The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 495-505 doi: 10.1007/s11684-020-0790-9

Abstract: explore the effect and mechanisms of the treatment plan of “traditional Chinese medicine (TCM) regulating liverA total of 457 patients with HBV-related liver failure were retrospectively collected.In addition, there were significant differences in the expression of several cytokines related to liverRLR treatment can decrease jaundice, improve liver function, and significantly reduce the mortality inpatients with HBV-related liver failure.

Keywords： hepatitis B virus-related liver failure     traditional Chinese medicine     liver regeneration     liver regeneration    

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FMO3--TMAO axis modulates the clinical outcome in chronic heart-failure patients with reduced ejection

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 295-305 doi: 10.1007/s11684-021-0857-2

Abstract: The association among plasma trimethylamine-N-oxide (TMAO), FMO3 polymorphisms, and chronic heartfailure (CHF) remains to be elucidated.

Keywords： chronic heart failure     trimethylamine-N-oxide     flavin monooxygenase 3     single nucleotide polymorphism    

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Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 421-427 doi: 10.1007/s11684-012-0223-5

Abstract:

In order to assess the value of liver volumetry in cirrhosis and acute liver failure (ALF) patientsto get a regression formula for standard liver volume (SLV) and BSA.It turned out that the mean liver volume of the control group was 1 058±337 cm3.Child A, B level was not reduced, but in Child C level it was significantly reduced with the lowest liverIn conclusion, the CTLV/SLV ratio, which reflects liver volume variations, correlates well with the liver

Keywords： liver volume variation     cirrhosis     acute liver failure (ALF)    

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Bioartificial liver devices: Perspectives on the state of the art

Yi-Tao DING, MM, Xiao-Lei SHI, MD

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 15-19 doi: 10.1007/s11684-010-0110-x

Abstract:

Acute liver failure remains a significant cause of morbidity and mortality.Bioartificial liver (BAL) devices have been in development for more than 20 years.Such devices aim to temporarily take over the metabolic and excretory functions of the liver until thepatients’ own liver has recovered or a donor liver becomes available for transplant.failure, and may also be a bridge to liver transplantation.

Keywords： acute liver failure     bioartificial livers     hepatocyte     bioreactor    

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Clinical characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 111-125 doi: 10.1007/s11684-021-0854-5

Abstract: Although mixed liver impairment has been reported in COVID-19 patients, the association of liver injurycaused by specific subtype especially chronic hepatitis B (CHB) with COVID-19 has not been elucidatedIn addition to previously reported liver impairment markers, such as alanine aminotransferase, aspartate

Keywords： COVID-19     chronic hepatitis B     liver injury     coagulation dysfunction    

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Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation

SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 167-172 doi: 10.1007/s11684-007-0031-5

Abstract: An independent association between acute renal failure (ARF) and intra-abdominal hypertension (IAH) afterliver transplantation has not been established previously.This study involved 62 subjects who underwent liver transplantation.IAH impaired renal function and was an independent risk factor for ARF after liver transplantation.
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A rare chronic constrictive pericarditis with localized adherent visceral pericardium and normal parietal

Qingqiang Ni,Lin Yun,Rui Xu,Guohua Li,Yucai Yao,Jiamin Li

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 356-359 doi: 10.1007/s11684-016-0467-6

Abstract: The patient presented with unexplained right heart failure and echocardiography showed moderate bi-atrialAfter 10 months of conservative treatment, the progression of right heart failure was remaining.This case serves as a reminder to consider CP in patients with unexplained right heart failure, so that

Keywords： constrictive pericarditis     heart failure     pericardiectomy    

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Severe hepatoxicity caused by aspirin overdose: a case report

Zhuping Cao,Shiqi Liu,Jianhua Niu,Bing Wei,Jie Xu

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 388-391 doi: 10.1007/s11684-015-0398-7

Abstract: Two years later, the patient died of chronic liver failure.

Keywords： aspirin     side effects     liver failure    

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Gut Microbiota-Controlled Tryptophan Metabolism Improves D-Gal/LPS-Induced Acute Liver Failure in C57BL Article

Zhipeng Zheng, Li Wu, Yuqiu Han, Jun Chen, Shuai Zhu, Yuanyuan Yao, Baohong Wang, Lanjuan Li

Engineering 2022, Volume 14, Issue 7,   Pages 134-146 doi: 10.1016/j.eng.2020.12.013

Abstract:

Acute liver failure (ALF) has an abrupt onset with a frequently fatal outcome.Previous studies have found that oral antibiotics prevent drug-induced liver injury in animal experimentssequencing showed that inflammatory responses were inhibited and metabolic pathways were upregulated in the liver

Keywords： Gut microbiota     Antibiotic     Tryptophan     Kynurenine     Aryl hydrocarbon receptor     Acute liver failure    

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New perspective on the natural course of chronic HBV infection

Yong-Yuan Zhang,Ke-Qin Hu,Zhongping Duan

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 129-134 doi: 10.1007/s11684-014-0339-x

Abstract:

Chronic hepatitis B virus (HBV) infection is a significant threat to public health and an enormousMechanisms responsible for chronic HBV infection remain poorly understood.A better understanding of the natural course of chronic HBV infection may shed new light on the mechanismsNatural course of chronic HBV infection is conventionally viewed as an uninterrupted process that isand reinfection, and such cycles prolong the chronic HBV infection course.

Keywords： hepatitis B virus     chronic HBV infection     natural course     hepatitis B     seroconversion    

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Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 1-7 doi: 10.1007/s11684-010-0105-7

Abstract:

Partial liver transplantation, including reduced-size liver transplantation, split liver transplantation, and living donor liver transplantation, has been developed with several innovative techniques becauseSplit liver transplantation provides chances to two or even more recipients when only one liver graftBefore surgery, a series of donor evaluations—including anatomical, liver volume, and liver functionAt different recipient conditions, auxiliary liver transplantation and auxiliary partial orthotopic liver

Keywords： partial liver transplantation     reduced-size liver transplantation     split liver transplantation     living donorliver transplantation    

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Title Author Date Type Operation

Overview on acute-on-chronic liver failure

Jing Zhang,Shan Gao,Zhongping Duan,Ke-Qin Hu

Journal Article

Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Journal Article

Correlation between viral load and liver cirrhosis in chronic hepatitis B patients

Lili LIU MM , Jiyao WANG MD , Weimin SHE MM ,

Journal Article

Advances in some common chronic liver diseases

Ke-Qin Hu

Journal Article

The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Journal Article

FMO3--TMAO axis modulates the clinical outcome in chronic heart-failure patients with reduced ejection

Journal Article

Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Journal Article

Bioartificial liver devices: Perspectives on the state of the art

Yi-Tao DING, MM, Xiao-Lei SHI, MD

Journal Article

Clinical characteristics and risk factors of COVID-19 patients with chronic hepatitis B: a multi-center

Journal Article

Intra-abdominal hypertension is an independent cause of acute renal failure after orthotopic liver transplantation

SHU Ming, PENG Chenghong, CHEN Hao, SHEN Boyong, ZHOU Guangwen, SHEN Chuan, LI Hongwei

Journal Article

A rare chronic constrictive pericarditis with localized adherent visceral pericardium and normal parietal

Qingqiang Ni,Lin Yun,Rui Xu,Guohua Li,Yucai Yao,Jiamin Li

Journal Article

Severe hepatoxicity caused by aspirin overdose: a case report

Zhuping Cao,Shiqi Liu,Jianhua Niu,Bing Wei,Jie Xu

Journal Article

Gut Microbiota-Controlled Tryptophan Metabolism Improves D-Gal/LPS-Induced Acute Liver Failure in C57BL

Zhipeng Zheng, Li Wu, Yuqiu Han, Jun Chen, Shuai Zhu, Yuanyuan Yao, Baohong Wang, Lanjuan Li

Journal Article

New perspective on the natural course of chronic HBV infection

Yong-Yuan Zhang,Ke-Qin Hu,Zhongping Duan

Journal Article

Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Journal Article